Health Condition 1: M350- Sicca syndrome [Sjogren]
Conditions
Interventions
Intervention1: Oral Melatonin in the management of hyposalivation associated with Sjogrens syndrome: The study group will receive tablet melatonin 5 mg once a day for 2 weeks
Control Intervention1: Me
Sponsors
Dr GEETHANJALI D
Eligibility
Inclusion criteria
Inclusion criteria: Patients who satisfy the characteristic features of Sjogrens according to American European Consensus Sjogrens syndrome classification criteria Both Primary and Secondary Sjogrens syndrome Individuals within the age group of 20-60 years Both genders Willingness to participate in the study
Exclusion criteria
Exclusion criteria: Not willing to participate in study Clinically significant cardiopulmonary disease renal disease or gastrointestinal tract disease diabetes mellitus hypersensitivity to pilocarpine use clinically significant ocular disease Lactating or pregnant women Allergic patients, immunocompromised patients. Past history of head and neck radiation treatment. Acquired immunodeficiency syndrome (AIDS) Current use of anticholinergic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of tablet Melatonin with tablet Pilocarpine in management of hyposalivation associated with Sjogren s syndrome.Timepoint: AT BASELINE 1 WEEK 2 WEEKS | — |
Secondary
| Measure | Time frame |
|---|---|
| Enhanced oral function,reducing dental caries,oral candidiasisTimepoint: At baseline,7thday,14th day | — |
Countries
India
Contacts
Public ContactDr GEETHANJALI D
Tamil Nadu Government Dental College and Hospital Chennai
Outcome results
None listed