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Comparison of two different cleaning protocol on gums and bone health and C reactive protein levels in severe periodontitis cases

Comparative study of C-reactive protein levels and periodontal outcomes in chronic periodontitis patient undergoing Non-Surgical Periodontal Therapy with subgingival irrigation of propolis extract versus chlorhexidine digluconate - A randomized controlled trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/102844
Enrollment
60
Registered
2026-02-03
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Propolis extract Irrigation: After full mouth ultrasonic scaling propolis extract subgingival irrigation will be done and the patient will be recalled for follow up Control Intervention

Sponsors

Dr Jha Sonuanand
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Chronic Periodontitis Probing pocket Depth 3-6mm No history of periodontal treatment in last 6 months No systemic disease affecting periodontal health

Exclusion criteria

Exclusion criteria: Systemic disease like diabetes, cardiovascular disease pregnant or lactating females current tobacco chewer or smoker allergy to propolis or chlorhexidine antimicrobial therapy during or before treatment pocket depth greater than 6 mm

Design outcomes

Primary

MeasureTime frame
Change in C reactive protein levels measured at baseline and 1 monthTimepoint: 6 months—

Secondary

MeasureTime frame
periodontal parameters measured at baseline 1 month and 3 monthsTimepoint: 6 months—

Countries

India

Contacts

Public ContactDr Nayana Patel

Government Dental College and Hospital Jamnagar

drnayanagpatel@gmail.com9825191911

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026