Comparison of Two Root Canal Cleaning Methods on Cleaning Depth and Post-Treatment Pain in Lower Molars

Comparative evaluation of depth of penetration of Irrigant and postoperative pain associated with Hebp/naocl versus naocl/edta in permanent Mandibular molars with symptomatic irreversible Pulpitis -a randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/102829

Enrollment

Registered

2026-02-03

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: K049- Other and unspecified diseases ofpulp and periapical tissues Health Condition 3: K040- Pulpitis

Interventions

Intervention1: HEBP+NaOCl: Twin kleen Intervention2: Naocl/Edta: Prevest Control Intervention1: Depth of penetration and postoperative pain in HEBP+NaOCl and NaOCl/EDTA: Postoperative pain in HEBP+NaO

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients between the ages of 18 and 50 years 2. Patients with diagnosis of symptomatic irreversible pulpitis in mandibular molars. 3. Teeth with pain score greater than 54 mm on Heft Parker visual analogue scale. 4. Healthy patients with ASAI and ASA II 5. Feasibility of isolating the tooth with a rubber dam. 6. Participants with the ability to understand the consent forms and the pain record scales.

Exclusion criteria

Exclusion criteria: 1. Non vital mandibular molars. 2. Teeth with calcified root canals, complex root canal anatomy and internal/external resorption. 3. Previously initiated root canal treatment. 4. Patients who had taken any analgesics or CNS depressents till before 12 hours of the treatment. 5. Mobile Teeth. 6. Teeth with pathologic periodontal pockets during probing.

Design outcomes

Primary

Measure	Time frame
Depth of Penetration of irrigant, Postoperative Pain and Analgesic intake Timepoint: 24 hours, 48 hours and 1 week	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Simran Bansal

J.N Kapoor DAV(c) Dental college

poonambogra@yahoo.in9050462962

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026