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A study comparing the effects of Injection Magnesium Sulphate and Injection Butorphanol when added to hyperbaric 0.5% Bupivacaine for spinal anesthesia in routine lower abdominal non-gynecological surgery.

A comparative study between intrathecal Magnesium Sulphate AND Butorphanol as adjuvants to hyperbaric 0.5 % Bupivacaine in elective infra-umbilical non-gynecological surgery. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/102765
Enrollment
50
Registered
2026-02-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C600- Malignant neoplasm of prepuce Health Condition 2: C679- Malignant neoplasm of bladder, unspecified Health Condition 3: K409- Unilateral inguinal hernia, without obstruction or gangrene Health Condition 4: K402- Bilateral inguinal hernia, withoutobstruction or gangrene Health Condition 5: K419- Unilateral femoral hernia, withoutobstruction or gangrene Health Condition 6: K458- Other specified abdominal hernia without obstruction or gangrene Health Condition 7: L768- Othe

Interventions

Intervention1: Group B will receive spinal anesthesia with single bolus dose of Injection Bupivacaine heavy + Injection Butorphanol as additive.: The study participants in group B will receive intrath

Sponsors

Department of Anesthesiology North Bengal Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients posted for elective non-gynecological infraumbilical surgery between age group of 20 years to 55 years of either sex of ASA 1 & 2 and BMI will be in between 18.5 to 24.9

Exclusion criteria

Exclusion criteria: 1.Patient refusal. 2.Patient with history of hypersensitivity to any of the medications being administered. 3.Patient undergoing gynecological surgery. 4.Pregnancy. 5.Patient with active cardiac,respiratory, renal ,neurological disorders and blood dyscrasias. 6.Patients with spinal deformities. 7.Patients with contraindication to spinal anesthesia.

Design outcomes

Primary

MeasureTime frame
BUTORPHANOL,AS AN ADJUVANT WITH HEAVY BUPIVACAINE IN INFRA-UMBILICAL SURGERIES,IS MORE EFFECTIVE FOR ONSET,INTRAOPERATIVE QUALITY OF BLOCK AND POST OPERATIVE ANALGESIA IN COMPARISON TO INJECTION MAGNESIUM SULPHATE WITH HEAVY BUPIVACAINE AS AN ADJUVANT.Timepoint: Time of onset of sensory block Time of onset of motor block Time of duration of sensory block Time of duration of motor block Time of total duration of surgery Time of first administration of rescue analgesic Total amount of analgesics at 6hrs after surgery.

Secondary

MeasureTime frame
Any abnormal findings pertaining to vitals i.e. BP ,Pulse, SpO2 after administration of spinal anesthesia. Any abnormal block dynamics, prolonged onset or duration of block to be noted.Any arrhythmias or inaadequacy of block duration to be noted.Any prolongation,inadequacy of block dynamics,any abnormality in vitals,any arrhythmias to be noted.Timepoint: The patients will be checked for onset & duration of both sensory & motor block in real time following administration of spinal anesthesia. Time of first rescue analgesia & total dose of rescue analgesia in first 6 hrs postoperatively will be noted.

Countries

India

Contacts

Public ContactDr. Abhishek Ganguly

North Bengal Medical College

abhi_here4u@yahoo.com9831404520

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026