Effect of Low Dose Dexmedetomidine in Reducing Muscle Pain After Electroconvulsive Therapy

Assessment of Effectiveness of inj. Dexmedetomidine (0.25mcg/kg) vs placebo to reduce succinylcholine induced myalgia in patients undergoing Electroconvulsive therapy: A randomized double blind controlled study. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/102748

Enrollment

Registered

2026-02-02

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F315- Bipolar disorder, current episodedepressed, severe, with psychotic features Health Condition 2: F333- Major depressive disorder, recurrent, severe with psychotic symptoms Health Condition 3: F428- Other obsessive-compulsive disorder Health Condition 4: F208- Other schizophrenia

Interventions

Intervention1: Inj. Dexmedetomidine: Intravenous 10 min before ECT Control Intervention1: INJ. Normal Saline: Intravenous 10 min before ECT

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade 2-3 undergoing ECT

Exclusion criteria

Exclusion criteria: Patients who dose not give written inform consent. Uncooperative patients. Patients with 2nd or 3rd degree heart block or persistant bradycardia. Patients on drugs such as beta blocker or antiarrhythmic drugs. Patients with history of allergic to study drugs. Pregnant or nursing mother.

Design outcomes

Primary

Measure	Time frame
Incidence of succinylcholine induced myalgia after ECT assessed using a 4 point myalgia grading scale (0= none, 1= mild, 2= moderate, 3= sever)Timepoint: After ECT 10min, 15min, 30min, 1hr, 2hr, 4hr, 6hr, 8hr	—

Secondary

Measure	Time frame
1. Severity of succinylcholine induced myalgia 2. Hemodynamic parameter(Heart rate, mean arterial pressure, Spo2%) 3. requirement of rescue analgesia 4. Adverse effectsTimepoint: After ECT 10min, 15min, 30min, 1hr, 2hr, 4hr, 6hr, 8hr	—

Countries

India

Contacts

Public ContactDr Pratik Khandhar

GMC Bhavnagar

drshilpadoshi@yahoo.in9428810763

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026