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A study comparing two medicines (Dexmedetomidine and Clonidine) to prevent nausea and vomiting after cochlear implant surgery in children.

Comparison of efficacy of Dexmedetomidine and Clonidine in preventing Post operative Nausea and Vomiting in paediatric patients undergoing Cochlear implant surgery - a triple blinded randomised controlled trial. - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/102733
Enrollment
48
Registered
2026-02-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H90- Conductive and sensorineural hearing loss Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Intravenous Dexmedetomidine: The child will receive IV dose of 0.5 mcg/kg of Dexmedetomidine infusion made to a volume of 20 ml by using normal saline over 10 minutes before extubation.

Sponsors

All India Institute Of Medical Sciences AIIMS Jodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Paediatric patients belonging to the group of ASA I/II and in the age group of 1-7 years scheduled to undergo cochlear implant surgery.

Exclusion criteria

Exclusion criteria: 1. ASA III/IV 2. Refusal of the consent by the parents/guardians. 3. Patients with known hypersensitivity to any of the study drugs. 4. Patients with history of motion sickness who are receiving antiemetic drugs before surgery. 5. Patients on medications with antiemetic properties

Design outcomes

Primary

MeasureTime frame
To compare Dexmedetomidine and Clonidine for reducing Post operative nausea vomiting in children undergoing cochlear implant surgery. Timepoint: Immediate Post op - Recovery at 0 min, 15 min and 30 min

Secondary

MeasureTime frame
1. To evaluate emergence delirium using the PAED scale and postoperative pain using the FLACC scale. 2. To assess the need for rescue antiemetic administration. 3. To monitor and document complications such as hypotension and bradycardia. Timepoint: Immediate Post op - Recovery at 0 min, 15 min and 30 min

Countries

India

Contacts

Public ContactShilpa Goyal

Department of Anaesthesiology and Critical Care, AIIMS Jodhpur

drshilpagoyal@yahoo.com8003996880

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026