Health Condition 1: M968- Other intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified
Conditions
Interventions
Intervention1: POMEGRANATE AND GRAPEFRUIT SEED EXTRACT CONTAINING MOUTHWASH.: PATIENTS WILL BE ADVISED TO RINSE WITH MOUTHWASH CONTAINING POMEGRANATE AND GRAPEFRUIT SEED EXTRACT FROM DAY ONE OF RADIOT
Sponsors
Dr ZEENA GUPTA
DR SHILPA K JAIN
Eligibility
Inclusion criteria
Inclusion criteria: Patients who are willing to participate in the study and sign the written consent. Patients who are diagnosed with histopathologically proven malignancy of oral cavity. Patients who have been scheduled for postoperative external beam radiation therapy. The patients who are receiving radiation therapy for the first time. The patients who are scheduled to receive a total radiation dose ranging between 60 and 70 Gy. The total duration of external beam radiation therapy should be not less than 6 weeks period delivered at 30 fractions. Patients who are willing to come for weekly evaluation.
Exclusion criteria
Exclusion criteria: Patients not willing to participate in the study. Patients with prior history of radiotherapy for any malignancy. Patients who have received prior chemotherapy for the management of any past or present malignancy. Patients diagnosed with Oral Submucous Fibrosis. Patients having any systemic illnesses and taking medications for the same especially diabetes mellitus, hypertension, renal disorders, hepatic disorders, haematological disorders, immunological disorders, gastrointestinal disorders, etc. Patients experiencing xerostomia and oral sores due to ill fitting dentures. Patients taking analgesics for other medical conditions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome of the Study: - The result of the study will help to determine whether extracts of pomegranate and grapefruit seed can be considered as effective prophylactic and preventive measure for radiation induced oral mucositis.Timepoint: Six weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| It will also help reduce the medications which are currently being used for palliative care among patients with radiation induced oral mucositis. It will also reduce the hospitalization duration, and overall increase the patient s quality of life by preventing or reducing RIOM.Timepoint: Six weeks | — |
Countries
India
Contacts
Public ContactDr ZEENA GUPTA
GOVERNMENT DENTAL COLLEGE, RAIPUR
Outcome results
None listed