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The main outcome of the study is to observe changes in diameter of optic nerve sheath after Pneumoperitoneum and Trendelenburg position in participants undergoing Total Laparoscopic Hysterectomy under General Anaesthesia

Changes in Ultrasound guided Optic Nerve Sheath Diameter after Pneumoperitoneum and Trendelenburg position in patients undergoing Total Laparoscopic Hysterectomy under General Anaesthesia -A longitudinal study. - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/02/0103551
Enrollment
60
Registered
2026-02-10
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nil: Nil Intervention2: NIL: NIL

Sponsors

NKP Salve Institute of Medical Sciences and Research centre and Lata Mangeshkar Hospital Nagpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients satisfying American Society of Anesthesiologist (ASA) Grade 1,2 and 3. Those who provided consent for participation in the study.

Exclusion criteria

Exclusion criteria: Patients with Diabetic Retinopathy. Chronic Obstructive Lung Disease(COPD) or Lung diseases with pulmonary hypertension History of ocular surgery. History of Intracranial surgery.

Design outcomes

Primary

MeasureTime frame
There are changes in the optic nerve sheath diameter due to pneumoperitoneum and Trendelenburg position in patients undergoing Total Laparoscopic Hysterectomy under General AnaesthesiaTimepoint: T0- Before induction (Baseline) T1- 5 minutes after Endotracheal intubation T2- 5 minutes after Trendelenburg position T3- 5 minutes after pneumoperitoneum in Trendelenburg position T4- 30 minutes after pneumoperitoneum in Trendelenburg position T5- 60 minutes after pneumoperitoneum in Trendelenburg position T6- 90 minutes after pneumoperitoneum in Trendelenburg position T7-120 minutes after pneumoperitoneum in Trendelenburg position T8- After extubation T9- 1 hour after extubation T10- 2 hours after extubation—

Secondary

MeasureTime frame
Association between increased Optic Nerve Sheath Diameter & occurrence of complications like headache, blurring of vision, nausea & vomiting, cognitive impairmentTimepoint: First 24 hours after surgery—

Countries

India

Contacts

Public ContactDr Roshni Dhomane

NKP Salve Institute of Medical Sciences and Research centre and Lata Mangeshkar Hospital, Nagpur

drketaki_didolkar@yahoo.co.in9850967274

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026