Comparison of Root canal cleaning solutions used in milk teeth of children.

Comparative antimicrobial efficacy and clinical success of saline, chlorhexidine, one percent sodium hypochlorite and MTAD as intracanal irrigants in primary molar pulpectomy A randomised controlled clinical trial - NIL

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/102638

Enrollment

160

Registered

2026-01-30

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Normal Saline irrigation: Pulpectomy will be performed in primary molars under rubber dam isolation. Biomechanical preparation will be carried out using hand and rotary files. Irrigatio

Eligibility

Inclusion criteria

Inclusion criteria: Children aged four to nine years of age Primary molars indicated for pulpectomy Teeth with minimum two thirds root length remaining Physiological root resorption not exceeding one third of root length Restorable primary molars with adequate coronal structure Written informed consent from parent or guardian

Exclusion criteria

Exclusion criteria: Children with systemic illness affecting healing or immunity. History of allergy to saline, chlorhexidine, sodium hypochlorite or MTAD Teeth with pathological root resorption, root perforation non restorable crown structure, excessive mobility, extensive furcal bone loss Previously endodontically treated teeth Children on antibiotics within past two or four weeks

Design outcomes

Primary

Measure	Time frame
Reduction in intracanal bacterial load, assessed by microbiological analysis of root canal samples collected before irrigation and immediately after final irrigation using sterlie papaer points.Timepoint: Before and after irrigation	—

Secondary

Measure	Time frame
Clinical success of pulpectomy at three and six months defined by the absence of spontaneous pain, swelling,sinus tract, tenderness to percussion or pathological mobilityTimepoint: clinical success at three months and six months;Radiographic success at three and six months determined by absence or reduction of furcal or periapical radiolucency, no evidence of pathological root resorption and normal development of the permanent successor .Timepoint: Radiographic success at three months and six months.;Post operative pain within the first seventy two hours following treatment, evaluated using age appropriate pain assessment scale.Timepoint: Seventy two hours after treatment	—

Measure

Time frame

Clinical success of pulpectomy at three and six months defined by the absence of spontaneous pain, swelling,sinus tract, tenderness to percussion or pathological mobilityTimepoint: clinical success at three months and six months;Radiographic success at three and six months determined by absence or reduction of furcal or periapical radiolucency, no evidence of pathological root resorption and normal development of the permanent successor .Timepoint: Radiographic success at three months and six months.;Post operative pain within the first seventy two hours following treatment, evaluated using age appropriate pain assessment scale.Timepoint: Seventy two hours after treatment

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Countries

India

Contacts

Public ContactKhushi Parmar

Saveetha Dental College and Hospitals , Chennai

rameshr.sdc@saveetha.com9895725236

Outcome results