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A Prospective Randomized Study Comparing the Efficacy of Nebulized Dexmedetomidine and Nebulized Magnesium Sulphate in Attenuating the Hemodynamic Response to Laryngoscopy and Tracheal Intubation

A prospective randomised study to compare the efficacy of Nebulized Dexmedetomidine and Nebulized Magnesium Sulphate for Attenuation of Hemodynamic Response during Laryngoscopy and Tracheal Intubation - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/102624
Enrollment
93
Registered
2026-01-30
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nil: Nil

Sponsors

Adesh Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists (ASA) grade I or II. 2. Age 18 60 years. 3. Elective surgery under general anesthesia requiring laryngoscopy and intubation

Exclusion criteria

Exclusion criteria: 1. Patient refusal. 2. Contraindications to these drugs. 3. History of difficult airway MPS grade 3/4 or failed intubation. 4. Chronic use of sedatives, oral magnesium supplements.

Design outcomes

Primary

MeasureTime frame
To compare the effectiveness of nebulised magnesium sulfate and dexmedetomidine by measuring changes in heart rate , Systolic BP , Diastolic BP and Mean BP during and after laryngoscopyTimepoint: 18 Months

Secondary

MeasureTime frame
1.To estimate the incidence of postoperative sore throat & other side effects. 2.To assess serum magnesium levels in all the groups Timepoint: 18 months

Countries

India

Contacts

Public ContactRohit Kumar

Adesh Medical College and Hospital Mohri Kurukshetra

ajaywahi81@yahoo.com9530582189

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026