A study comparing two strengthening exercise programs for reducing pain and improving function in people with Knee Arthritis

Comparative effectiveness of hip versus foot-ankle muscle strengthening combined with conventional knee exercises on pain and function in knee osteoarthritis: A randomized clinical trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/102588

Enrollment

Registered

2026-01-30

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M171- Unilateral primary osteoarthritisof knee

Interventions

Intervention1: Strengthening exercises: Group A will undergo an 8 week foot ankle muscle strengthening program combined with conventional knee exercises. Group B will receive an 8 week hip muscle stre

Eligibility

Inclusion criteria

Inclusion criteria: Individuals diagnosed with unilateral knee osteoarthritis who fulfilled the American College of Rheumatology (ACR) criteria based on both clinical and radiographic findings. All participants reported knee pain associated with age over 50 years,morning stiffness lasting less than 30 minutes, and crepitus during active knee movement. Radiographic severity of knee osteoarthritis was classified as Grade 2 or Grade 3 according to the Kellgren and Lawrence scale. Additionally, participants had knee pain intensity ranging from 30 to 80 mm on the Visual Analogue Scale (VAS) and a body mass index (BMI) of less than 35 kg/m .

Exclusion criteria

Exclusion criteria: Individuals with cognitive impairment or a history of intra-articular knee injections, specifically hyaluronic acid injections within the previous six months or corticosteroid injections within the last three months. Participants with a history of knee, hip, or ankle surgery within the past two years were excluded. Those who used external support for ambulation or had severe knee valgus or varus deformities requiring assistive devices were not included. Individuals with neurological conditions affecting lower-limb function, rheumatoid arthritis involving the knee joint, or asymptomatic knee osteoarthritis.

Design outcomes

Primary

Measure	Time frame
VAS WOMACTimepoint: Baseline, 8 weeks( post-intervention ), 16 weeks (Follow up )	—

Secondary

Measure	Time frame
TUG testTimepoint: Baseline, 8 weeks(post-intervention),16 weeks (follow up)	—

Countries

India

Contacts

Public ContactANANDESHI PRIYANKA

INSTITUTE OF PHYSIOTHERAPY, SRINIVAS UNIVERSITY

drajay@srinivasuniversity.edu.in7019238290

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026