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Comparing Two Root Canal Cleaning liquids and Techniques to Reduce Infection in Teeth

Comparative evaluation in decreasing bacterial load after using 5.25 percent Sodium hypochlorite and 2 percent Chlorhexidine with Sonic and LASER irrigation activation system An In vivo study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/102585
Enrollment
60
Registered
2026-01-30
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Group 1 ( Naocl + sonic): 5.25 % Sodium hypochlorite with sonic activation Intervention2: Group 2 ( Naocl + Laser): 5.25% Sodium hypochlorite with Laser activation Intervention3: Group

Sponsors

Dr Priya Naikwade
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Single-rooted teeth indicated for root canal treatment. 2)Diagnosed with pulpal and peri-radicular diseases. Patients aged 18 45 years. 3)Patients suitable for routine endodontic therapy.

Exclusion criteria

Exclusion criteria: 1)Fractured or badly decayed teeth that cannot be isolated with a rubber dam. 2) Immature apices. 3) Medically compromised patients.

Design outcomes

Primary

MeasureTime frame
Reduction in intracanal bacterial load (measured as colony-forming units per millilitre [CFU/mL]) after irrigation using 5.25% sodium hypochlorite and 2% chlorhexidine with different irrigation activation systems (conventional, sonic, and laser) during root canal treatment.Timepoint: 1 Day—

Secondary

MeasureTime frame
1.Comparison between irrigation activation systems: Evaluate & compare the antibacterial efficacy of sonic & laser irrigation activation systems in reducing bacterial load from root canals. Outcome measure: Difference in mean CFU/mL reduction between sonic & laser groups. 2.Comparison between irrigants: Evaluate & compare the antibacterial efficacy of 5.25% sodium hypochlorite & 2% chlorhexidine solutions within each activation system. Outcome measure: Difference in mean CFU/mL reduction between NaOCl & CHX within the same group.Timepoint: 1 Day—

Countries

India

Contacts

Public ContactDr Bharat Deosarkar

Saraswati Dhanwantari Dental college, Parbhani

deosarkar.bharat16@gmail.com9975581234

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026