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Dextrose versus Triamcinolone Injection for Carpal Tunnel Syndrome Relief

A Randomized Controlled Trial Comparing the Efficacy of Five Percent Dextrose and Triamcinolone Hydrodissection for Carpal Tunnel Syndrome - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/102488
Enrollment
110
Registered
2026-01-29
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G560- Carpal tunnel syndrome

Interventions

Intervention1: Ultrasound guided median nerve hydrodissection using five percent dextrose. : Dextrose group will receive a single 10 millilitre perineural injection prepared by mixing 2 millilitres o
follow-up assessments at 1 and 3 months. Control Intervention1: Ultrasound guided median nerve hydrodissection using forty milligrams per milliliter triamcinolone acetate.: Triamcinolone group will re

Sponsors

AIIMS Jodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with mild to moderate carpal tunnel syndrome based on electrophysiological studies and meeting the following criteria. Primary symptom includes nocturnal paresthesia or dysesthesia in the affected hand, possibly associated with hand posture, overuse, or relief by shaking the hand, also known as the flick sign. At least one of the following features must be present. Numbness in the median nerve sensory distribution of the hand. Weakness with atrophy of the thenar muscles. Positive Phalen s sign or Tinel s sign.

Exclusion criteria

Exclusion criteria: Pre existing neurological conditions such as polyneuropathy, brachial plexopathy, or thoracic outlet syndrome. Recent wrist surgery. Inflammatory conditions such as rheumatoid arthritis, hypothyroidism, or other rheumatological disorders. Pregnancy. Uncontrolled diabetes mellitus. Current warfarin use or previous steroid injections at the wrist. Any trauma, tumor, or infection at the injection site. Allergy to corticosteroids or lidocaine.

Design outcomes

Secondary

MeasureTime frame
boston carpal tunnel questionnaireTimepoint: base line 1 month and 3 month;cross sectional area of median nerve in ultrasoundTimepoint: base line 1 month 3 month;nerve conduction studiesTimepoint: base line 1 month and 3 month;grip strength of handTimepoint: base line 1 month and 3 month

Primary

MeasureTime frame
Visual analog scale (VAS)Timepoint: base line 1 month and 3 month

Countries

India

Contacts

Public ContactDr Ravi Gaur

All India Institute Of Medical Sciences Jodhpur

ravisms80@gmail.com8299711753

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026