Use of intramuscular Glycopyrrolate in prevention of spinal anaesthesia induced hypotension in elective cesarean section.

Pre-emptive intramuscular Glycopyrrolate in prevention of spinal anaesthesia induced hypotension in elective cesarean section: A randomized controlled trial. - nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/102464

Enrollment

100

Registered

2026-01-29

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nil: Nil Intervention2: Pre-emptive intramuscular Glycopyrrolate before spinal anaesthesia: Group A (IM Glycopyrrolate group): This group will consist of 50 patients who will receive in

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 18 60 years of either sex. 2. American Society of Anesthesiologists (ASA) physical status class I and II. 3. Patient undergoing elective surgery under General Anaethesia requiring endotracheal intubation.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
To compare the Systolic blood pressure, diastolic blood pressure and mean arterial blood pressure between two groupsTimepoint: recorded every 3 min intervals until 15 min and at 5 min intervals thereafter until 60 min	—

Secondary

Measure	Time frame
To compare the heart rate between two groupsTimepoint: recorded every 3 min intervals until 15 min and at 5 min intervals thereafter until 60 min;Total amount of blood loss in surgeryTimepoint: ;Post-operative assessment of Systolic blood pressure, diastolic blood pressure and mean arterial blood pressure between two groupsTimepoint: recorded every 30 min until 180 min;Side effects including dry throat, nausea, vomiting and any other adverse effectTimepoint:	—

Measure

Time frame

To compare the heart rate between two groupsTimepoint: recorded every 3 min intervals until 15 min and at 5 min intervals thereafter until 60 min;Total amount of blood loss in surgeryTimepoint: ;Post-operative assessment of Systolic blood pressure, diastolic blood pressure and mean arterial blood pressure between two groupsTimepoint: recorded every 30 min until 180 min;Side effects including dry throat, nausea, vomiting and any other adverse effectTimepoint:

—

Countries

India

Contacts

Public ContactDr Vibha Mehta

Maharaja agrasen medical college

drvibhamehta1@gmail.com9466088221

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026