A comparison of two medicines that is Dexmedetomidine and Midazolam added to local anaesthetic to make forearm surgeries more comforatble and pain free .

A prospective,randomized,double blind study to compare between Dexmedetomidine and Midazolam as an adjuvant to Bupivacaine (0.5 percent) in ultrasound guided supraclavicular brachial plexus block for forearm surgeries - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/102408

Enrollment

Registered

2026-01-29

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S520- Fracture of upper end of ulna Health Condition 2: S518- Open wound of forearm Health Condition 3: S562- Injury of other flexor muscle, fascia and tendon at forearm level Health Condition 4: S621- Fracture of other and unspecifiedcarpal bone(s)

Interventions

Intervention1: DEXMEDETOMIDINE: Adding Dexmedetomidine 1 microgram per kg body weight as an adjuvant to Bupivacain (0.5 percent) 15 ml as a single dose in ultrasound guided Supraclavicular brachial pl

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologist (ASA) physical status I or II, Weight more than 40 kg, Those willing to participate in the study.

Exclusion criteria

Exclusion criteria: Patient refusal, Study drug contraindicated or Contraindications to regional anaesthesia, Patients with coagulation disorders,local Skin infection, those who are morbidly obese, hemodynamically unstable, ASA Physical status more than II.

Design outcomes

Primary

Measure	Time frame
Duration of analgesia.Timepoint: From Local Anesthetic administration to 2,4,6,8,10,12,18hours till complete recovery of anesthesia on all nerves and complete recovery of Motor function of the hand and the forearm.	—

Secondary

Measure	Time frame
Onset of AnalgesiaTimepoint: from Local Anaesthetic administration to the onset of analgesia at 5,10,15,20 minutes.;Hemodynamic changes like Heart rate, Systolic blood pressure,Diastolic blood pressure, SPO2Timepoint: From Local Anaesthetic Administration to 5,10,15,30,60 minutes and every half hourly thenafter	—

Countries

India

Contacts

Public ContactDr SUREKHA VYANKATRAO MORE

Vilasrao Deshmukh Government Medical College,Latur

desurekha@gmail.com9422741346

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026