Effect of Brahmi leaf Extract in Hypothyroidism

An Open-Label, Active-Controlled, Parallel-Group Clinical Study to Evaluate the Efficacy of Brahmi (Bacopa Monneri L.) Leaf Extract as an Adjuvant Therapy in Primary Hypothyroidism. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/102406

Enrollment

Registered

2026-01-29

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E039- Hypothyroidism, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Clinically diagnosed cases of primary hypothyroidism Patients willing to give written informed consent Diagnosis confirmed by Zulewski clinical score and Thyroid Symptom Questionnaire Serum TSH value more than 4.5 mIU per L Total serum T3 and T4 values below or within normal laboratory range Total T3 range 0.83 to 2.00 ng per mL Total T4 range 52 to 127 nmol per L

Exclusion criteria

Exclusion criteria: History of thyroid surgery Hashimoto thyroiditis Immunocompromised conditions Active infectious diseases such as tuberculosis or hepatitis B Pregnant or lactating women Participation in any other clinical trial within the last two months Congenital hypothyroidism Secondary hypothyroidism

Design outcomes

Primary

Measure	Time frame
To evaluate changes in serum T3, T4, and TSH levels and improvement in clinical symptoms of hypothyroidism in patients after intervention with Brahmi extractTimepoint: Serum T3, T4, and TSH will be assessed at baseline and at Visit 4, while clinical symptom assessment will be done at baseline and during Visit 1,Visit 2, Visit 3 and Visit 4.	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Haresh Soni

Parul Institue of Ayurved

drhareshsoni71@gmail.com7878374848

Outcome results