Safety and usefulness of the Ayurvedic Formulation Vasaguduchyadi Ghanavati in Fatty Liver Disease (not Alcoholic)

Pharmacognostic and Phytochemical Standardization of Vasaguduchyadi Ghanavati and its Preclinical Safety and Clinical Efficacy in Non-Alcoholic Fatty Liver Disease - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/102346

Enrollment

Registered

2026-01-28

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K739- Chronic hepatitis, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age between 18 to 60 years 2. Diagnosed with Grade 1 or Grade 2 NAFLD, confirmed by ultrasonography. 3. Presenting with clinical symptoms such as fatigue, indigestion or anorexia 4. Willingness to participate in the trial and provide written informed consent

Exclusion criteria

Exclusion criteria: 1. History of Alcohol intake more than 20gm per day. 2. Presence of viral hepatitis (HBV, HCV),autoimmune hepatitis, or decompensated cirrhosis. 3. Ongoing use of hepatotoxic medications or participation in another clinical trial. 4.Pregnancy or lactation.

Design outcomes

Primary

Measure	Time frame
Improvement in hepatic steatosis (graded by abdominal ultrasonography) Reduction in serum ALT and AST levels (markers of liver inflammation)Timepoint: 90 days	—

Secondary

Measure	Time frame
Changes in ALP, serum bilirubin, fasting glucose, and lipid profile Hematological parameters (Hb, TLC, platelet count, ESR) Subjective symptoms (e.g., appetite, fatigue, digestion) using a validated symptom severity scoring system Adverse events and safety profile as per WHO causality assessment criteriaTimepoint: 90 days	—

Countries

India

Contacts

Public ContactJishma Saha

Institute of Post Graduate Ayurvedic Education and Research at SVSP Hospital

atipgaer@gnail.com9874849650

Outcome results