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The blood vessel changes for prediction of aggressiveness of oral squamous cell carcinoma as compared to routine guidelines.

Assessing the utility of CD 34 expression as an immunohistochemical marker for tumor behaviour in comparison to histopathological parameters and Tumour, Lymph nodes, Metastasis staging in oral squamous cell carcinoma. - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/01/102329
Enrollment
50
Registered
2026-01-28
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C060- Malignant neoplasm of cheek mucosa Health Condition 2: C069- Malignant neoplasm of mouth, unspecified Health Condition 3: C068- Malignant neoplasm of overlappingsites of other and unspecified parts of mouth Health Condition 4: C062- Malignant neoplasm of retromolar area

Interventions

Control Intervention1: NIL: NIL

Sponsors

Datta Meghe Institute of Higher Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Already diagnosed cases of oral squamous cell carcinoma on Histopathology. All cases with Composite resection of lesion plus suitable Modified radical neck dissection (MRND) plus reconstruction with microvascular flap Primary cases of Oral squamous cell carcinoma without any history of previous treatment. All patients with oral squamous cell carcinoma arising Denovo

Exclusion criteria

Exclusion criteria: All cases of benign lesions of oral cavity All cases of malignancy other than oral squamous cell carcinoma. All patients with oral squamous cell carcinoma where cancer is arising as a result of recurrence. Cases with previous history of chemotherapy and radiotherapy. All defaulted patients Patients with no histological confirmation of oral squamous cell carcinoma.

Design outcomes

Primary

MeasureTime frame
To assess the expression of CD 34 in oral squamous carcinoma and compare it with College of American Pathologists( CAP)guidelines.Timepoint: 2 years—

Secondary

MeasureTime frame
NilTimepoint: Nil—

Countries

India

Contacts

Public ContactDr Samarth Shukla

Datta Meghe Institute of Higher Education and Research

samarth21174@gmail.com8830267710

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026