Health Condition 1: G408- Other epilepsy and recurrent seizures
Conditions
Interventions
Intervention1: Memantine: 2-5-5 mg/day for children 6 years or younger and 5-10 mg/day for children older than 6 years in the form of oral tablets daily in one to two divided doses for eight weeks, al
Sponsors
Dr Vaibhav Kashyap
Eligibility
Inclusion criteria
Inclusion criteria: Children with developmental and epileptic encephalopathy
Exclusion criteria
Exclusion criteria: 1.History of allergy to memantine 2.Already using or used memantine previously 3.Parents not providing informed consent 4.Clinical evidence of any other major systemic illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of participants with a favourable responseTimepoint: 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of participants with improvement in EEGTimepoint: At 8 weeks;Number of participants achieving at least a 50 percent reduction in seizure frequency Timepoint: At 8 weeks;Parent Global Impression Improvement scoreTimepoint: At 8 weeks;Change in social quotientTimepoint: At baseline (0 week) and 8 weeks | — |
Countries
India
Contacts
Public ContactDr Vaibhav Kashyap
All India Institute of Medical Sciences, Rishikesh
Outcome results
None listed