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Comparison of platelet rich fibrin with and without stem cells for improving dental implant stability and bone strength A clinical and radiographic study

A comparative evaluation of the effect of platelet rich fibrin matrix with and without peripheral blood mesenchymal stem cells on dental implant stability and bone density: A clinico-radiographic study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/102301
Enrollment
20
Registered
2026-01-28
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K069- Disorder of gingiva and edentulousalveolar ridge, unspecified

Interventions

Intervention1: Dental implant placement with PRFM and PBMSCs: Peripheral Blood Mesenchymal Stem Cells embedded in Platelet Rich Fibrin Matrix will be placed into the osteotomy site and the dental impl

Sponsors

DrAmrutha KS
Lead Sponsor
Indian Society Of Periodontology
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age between 20-55 years. 2.Missing any 2 mandibular posterior teeth. 3.Adequate bone for the placement of conventional implants without the requirement of grafting . 4.Patients with good systemic health. 5.Patient having good oral hygiene and good compliance to the treatment.

Exclusion criteria

Exclusion criteria: 1.Patients under bisphosphonates corticosteroid therapy chemotherapy localized radiotherapy of the oral cavity were not included. 2.Patients with poor oral hygiene. 3.Para functional habits were excluded. 4.Patients with mucocutaneous lesions immunosuppression or any systemic diseases who have been contraindicated for any surgical procedures will not included. 5.Patients consuming excessive alcohol and or who smoke.

Design outcomes

Primary

MeasureTime frame
Implant stability quotientTimepoint: 1. At one week of implant placement 2. At 1 month of implant placement 3. At 3 months of implant placement

Secondary

MeasureTime frame
Bone densityTimepoint: It will be measured at mesial, distal, buccal, lingual and apical to the implant. At baseline and 3 months

Countries

India

Contacts

Public ContactDr Ghousia Fatima

Al Badar Rural Dental College And Hospital Kalaburagi

amrutha.kps1@gmail.com8296643758

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026