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PROSPECTIVE RANDOMIZED CONTROL DOUBLE BLINDED TRAIL ON PREOPERATIVE ORAL ZINC TABLET DECREASING INCIDENCE OF POSTOPERATIVE SORE THROAT

PROSPECTIVE RANDOMIZED CONTROL DOUBLE BLINDED TRAIL ON PREOPERATIVE ORAL ZINC TABLET DECREASING INCIDENCE OF POSTOPERATIVE SORE THROAT - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/102298
Enrollment
180
Registered
2026-01-28
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Zinc tablet: Giving zinc premedication to patients undergoing surgery under general anesthesia with endotracheal tube Control Intervention1: Placebo: Giving placebo tablet to patients u

Sponsors

Manipal hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American society of anesthesiologists grade 1 and 2 aged 18-60 years, posted for surgeries lasting greater than 1 hour and less than 6 hour duration under general anesthesia requiring tracheal intubation will be included for the study

Exclusion criteria

Exclusion criteria: 1. Smokers 2. Pregnant patients 3. Patients with recent history of sore throat 4. Malampatti grade greater than 2 5. Patients with zinc allergy 6. Traumatic or more than one attempt of intubation 7. Cormack-lehane score 3 and 4

Design outcomes

Primary

MeasureTime frame
Primary aim of our study will be to assess the incidence of POST at 4 hours after surgery after zinc 40mg premedicationTimepoint: Primary aim of our study will be to assess the incidence of POST at 4 hours after surgery after zinc 40mg premedication

Secondary

MeasureTime frame
NilTimepoint: Nil

Countries

India

Contacts

Public ContactDR VISHWANATH SIDDINI

MANIPAL HOSPITALS OLD AIRPORT ROAD

vishwanathsid@gmail.com9845174866

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026