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A study to compare the effect of Magnesium Sulfate Soaked gauze placed in throatand Intravenous Magnesium Sulfate for Preventing Sore Throat after Elective Nasal Surgery.

A Randomized, Double-Blind, Placebo-Controlled Trial Comparing Magnesium Sulfate Soaked Throat Packs versus Intravenous Magnesium Sulfate for Preventing Postoperative Sore Throat after Elective Nasal Surgery. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/102285
Enrollment
105
Registered
2026-01-28
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: compare the effect of Magnesium Sulfate Soaked Throat Packs versus Intravenous Magnesium Sulfate for Preventing Postoperative Sore Throat after Elective Nasal Surgery.: In the operation
Group I received IV magnesium sulphate with a normal saline soaked throat pack
and Group P received normal saline both topically and intravenously.: Randomisation will be done using computer generated random numbers for allocation of patients into three groups- T, I and P. Group

Sponsors

All India Institute of Medical Sciences Jodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adults (18-65 years) Scheduled for elective nasal surgery under general anaesthesia requiring placement of endotracheal tube and throat pack (Septoplasty, Functional Endoscopic Sinus Surgery, Septorhinoplasty), Duration of surgery between 60 to 180 minutes

Exclusion criteria

Exclusion criteria: History of recent upper respiratory tract infection or sore throat Anticipated difficult airway Patients who require more than one attempt at endotracheal intubation Traumatic intubation Preoperative use of analgesic medications (Paracetamol/NSAIDs/Opioids) within 24 hours of surgery Previous H/O any laryngotracheal disease Known allergy to study drug

Design outcomes

Primary

MeasureTime frame
To compare the incidence and severity of POST post-surgery using visual analogue scale (VAS) score Timepoint: At 2 hours postoperative—

Secondary

MeasureTime frame
Serum Magnesium levels at post insertion of throat pack in all the three groups Timepoint: at baseline, 1, 2 and 6 hours post insertion of throat pack;Incidence and severity of sore throatTimepoint: at 0, 4, 8 and 24 hours;Incidence and severity of hoarseness of voiceTimepoint: at 0, 2, 4, 8 and 24 hours ;Incidence and severity of coughTimepoint: at 0, 2, 4, 8 and 24 hours;Incidence and severity of dysphagiaTimepoint: at 0, 2, 4, 8 and 24 hours ;Incidence and severity of nausea and vomitingTimepoint: at 0, 2, 4, 8 and 24 hours;Any trauma, laryngospasm and bronchospasmTimepoint: in the immediate postoperative period—

Countries

India

Contacts

Public ContactDr Devendra Kumar

All India Institute of Medical Sciences Jodhpur

swati_virgo83@yahoo.co.in07340033034

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026