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Comparison of sedative effects of 2 drugs(dexmedetomidine and remifentanyl)in patients posted for heart valve replacement procedure done by cardiologists

Comparison of continuous infusion of dexmedetomidine vs remifentanyl for conscious sedation in patients undergoing transcatheter aortic valve replacement -a single blinded randomized control trial - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/01/102255
Enrollment
80
Registered
2026-01-28
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I350- Nonrheumatic aortic (valve) stenosis

Interventions

Intervention1: Nil: Nil

Sponsors

Medanta the medicity
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients more than 60 years with severe aortic stenosis with symptoms such as chest pain,palpitation and with preserved systolic funtion

Exclusion criteria

Exclusion criteria: recent MI or stroke within last 6 months,CAD,patients not giving consent,EF less than 60 percent

Design outcomes

Primary

MeasureTime frame
sedative effects (Ramsay Sedation Score)and hemodynamic parameters of both sedative effects and hemodynamic parameters of both remifentanyl and dexmedetomidine remifentanyl and dexmedetomidineTimepoint: 1 year—

Secondary

MeasureTime frame
postoperative delirium,postoperative nausea and vomiting,length of ICU and hospital stay,adverse events,conversion to GATimepoint: 1 year—

Countries

India

Contacts

Public ContactDr Christy Pius Kaliyadan

Medanta the medicity

Yatin.mehta@medanta.org9539747439

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026