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Prospective Observational Study of Lactate Albumin Ratio Versus CRP Albumin Ratio as Prognostic Biomarkers for 28-Day Mortality in Sepsis.

Lactate - Albumin Ratio vs C- reactive Protein Albumin Ratio as Predictors of 28 Day Mortality in Patients With Sepsis : A Prospective Observational Study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/01/102233
Enrollment
130
Registered
2026-01-28
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R688- Other general symptoms and signs

Interventions

Intervention1: Nil: Nil Control Intervention1: Nil: Nil

Sponsors

Prakriya hospitals
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult patients aged 18 years and above. 2. Patients diagnosed with sepsis including septic shock as per Sepsis-3 criteria diagnosed within 24 hours of ICU admission.

Exclusion criteria

Exclusion criteria: 1. Patients with chronic liver disease, nephrotic syndrome, CKD on dialysis, Pancreatitis, protein-losing enteropathy. 2. Pregnancy. 3. Patients with malignancy, severe malnutrition, or on immunosuppressive therapy. 4. Post Op surgical patients. 5. Patients who receive albumin infusion or blood transfusion within 24 hours prior to sampling. 6. Readmissions during the same hospital stay. 7. Patients or relatives who do not provide informed consent.

Design outcomes

Primary

MeasureTime frame
To compare the prognostic value of Lactate Albumin Ratio (LAR) and C-Reactive Protein Albumin Ratio (CAR) in predicting 28-day all-cause mortality within the first 24 hours of ICU admission among adult patients who are diagnosed with sepsis.Timepoint: Patient will be assessed for 28 days mortality

Secondary

MeasureTime frame
To assess the association of LAR and CAR with clinical outcomes like: 1. Duration of mechanical ventilation (ventilation free days), 2.requirement of vasopressors, 3.length of ICU 4.Length hospital stay. 5.28 day mortality. Timepoint: ;To compare LAR and CAR with other prognostic indices like APACHE2, SOFA, Pro calcitonin, CRP, Lactate, TLC, Albumin.Timepoint:

Countries

India

Contacts

Public ContactDr Somnath Chatterjee

Prakriya hospitals

meddirector@prakriyahospitals.com7259624270

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026