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A clinical trial to study the effects of a combination of two drugs, Magnesium Sulphate with Ropivacaine in Patients Undergoing Cervical Spine Surgery for Better Pain Control

Analgesic Effect of Magnesium Sulphate as an Adjuvant to Ropivacaine in Erector Spinae Plane Block in Cervical Spine Surgeries: A Randomized Controlled Trial. - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/102218
Enrollment
151
Registered
2026-01-28
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G55- Nerve root and plexus compressionsin diseases classified elsewhere

Interventions

Intervention1: Ultrasound-guided Cervical Erector Spinae Block (CESP Block): Three Groups: 1 Group R: 30 cc of 0.375 percent Ropivacaine plain in Ultrasound-guided Cervical Erector Spinae Block 2 Gr

Sponsors

Dr Madhusudhana Rao B
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1-3, History of cervical myelopathy, Presenting for elective cervical spine surgery with or without fusion

Exclusion criteria

Exclusion criteria: 1.Patients with heart rate or rhythm abnormalities 2.Re-exploration procedures 3.Patients on ventilator support in the preoperative period 4.Patients with bleeding disorder 5.patient in sepsis or recovered from sepsis or poor skin condition or local infection 6.Complete spinal cord injury 7.Pregnant or nursing mothers 8.Liver and renal disorders

Design outcomes

Primary

MeasureTime frame
Outcome Name: 1. Consumption of cumulative opioid and anaesthetic requirements. 2. Postoperative pain score-NRS for pain score Timepoint: Time-point: At 0 hour- Immediate postop, 1st hour, 2nd hour,3rd hour, 4th hour, 5th hour, 6th hour,8th hour, 10th hour, 12th hour, 24th hour,36th hour and 48th hour.

Secondary

MeasureTime frame
1. Time to ambulate postoperatively from the time of surgery. 2. Modified Observers Alertness or Sedation Score MOASS 3. Total satisfaction score Timepoint: 1. Time to ambulate postoperatively from the time of surgery. 2. Modified Observers Alertness or Sedation Score MOASS at- 0 hour Immediate postop 1st hour 2hour3hour 4hour 5hour 6hour 8hour 10hour 12th hour 24th hour 36th hour 48th hour. 3. Total satisfaction score at 48th hour.

Countries

India

Contacts

Public ContactDr Madhusudhana Rao B

Ramaiah Medical College and Hospitals

drbmadhusudhanrao15@gmail.com9048656800

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026