Study Comparing Two Different Steroid Treatment Methods in Kidney Transplant Rejection Patients

Comparison of Slow Tapering vs Maintenance Low-dose Steroid Regimens in the Management of T Cell-Mediated Rejection in Renal Transplant Recipients: Impact on Allograft Function and Urinary Biomarkers - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/102181

Enrollment

Registered

2026-01-27

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N288- Other specified disorders of kidney and ureter

Interventions

Intervention1: slow tapering steroid Regimen: Patients will receive standard pulse therapy followed by oral prednisone at a dose of 0.5 mg per kg per day (approximately 30 mg per day for a 60 kg patie

Eligibility

Inclusion criteria

Inclusion criteria: Comparsion of Change in serum creatinine from baseline to 1 week, 1 month, and 3 months in the two group

Exclusion criteria

Exclusion criteria: Changes in urinary biomarkers from baseline to 3 months Comparison of adverse events between groups

Design outcomes

Primary

Measure	Time frame
Comparsion of Change in serum creatinine from baseline to 1 week, 1 month, and 3 months in the two groupTimepoint: baseline at 1 week, 1 month, and 3 months in the two group	—

Secondary

Measure	Time frame
Changes in urinary biomarkers from baseline to 3 months Comparison of adverse events between groups Timepoint: baseline to 3 month	—

Countries

India

Contacts

Public ContactDrSmita Divyaveer G

Departement of Nephrology,Postgraduate Institue of Medical Education and Research(PGIMER)

divyaveer.ss@gmail.com8208839726

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026