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Effects of three different bolus doses of Norepinephrine for preventing low blood pressure during Spinal Anaesthesia for caesarean delivery. A Randomized Clinical Trial

Effects of three different bolus doses of Norepinephrine for preventing Hypotension during Spinal Anaesthesia for caesarean delivery. A Randomized Clinical Trial - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/102166
Enrollment
150
Registered
2026-01-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O746- Other complications of spinal andepidural anesthesia during labor and delivery

Interventions

Intervention1: Norepinephrine 10 Micrograms: Study participants will receive 10 micrograms of norepinephrine in case of hypotension induced during spinal anaesthesia for cesarean delivery.Duration of

Sponsors

Regional Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: AMERICAN SOCIETY OF ANAESTHESIOLOGISTS(ASA) PHYSICAL STATUS GRADE I OR II. PATIENTS UNDERGOING ELECTIVE CAESAREAN DELIVERY

Exclusion criteria

Exclusion criteria: 1 History of allergy to local anaesthetic agent and or study drugs 2 Bleeding disorders like Von Willebrand disease Idiopathic Thrombocytopenic purpura platelet count less than 50000 per microlitre prothrombin time less than 14 seconds International normalised ratio INR less than 1.5 3 Local site infection mainly spine 4 Spinal deformity 5 Cardiac respiratory diseases and kidney disorder and neurological deficit 6 Parturient with Pre eclamptic toxaemia or any hypertensive disorder

Design outcomes

Primary

MeasureTime frame
To determine the optimal bolus doses of norepinephrine in management of spinal hypotension in elective caesarean sectionTimepoint: At baseline—

Secondary

MeasureTime frame
To compare the hemodynamic parameters like Systolic blood pressure (SBP) Mean arterial pressure (MAP) Diastolic blood pressure (DBP) & heart rate (HR) at varied time interval after administration of norepinephrine & also the foetal cord blood acid base study at delivery & after 5 minutes Adverse effects like giddiness, nausea &vomiting. Timepoint: At baseline & After 5 minutes till 90 minutes—

Countries

India

Contacts

Public ContactDeepali Srivastava

Regional institute of medical sciences

takhelhem@yahoo.com9436021445

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026