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Comparison of Dexmedetomidine and Buprenorphine Added to Levobupivacaine for Nerve Block in Upper Limb Surgery

Comparative evaluation Of dexmedetomidine and buprenorphine as adjuvants to 0.5 percentage levobupivacine in ultrasound guided supraclavicular brachial plexus block for Upper Limb Surgeries a randomised control trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/102132
Enrollment
72
Registered
2026-01-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B- Imaging Health Condition 2: M796- Pain in limb, hand, foot, fingersand toes Health Condition 3: M796- Pain in limb, hand, foot, fingersand toes

Interventions

Intervention1: Levobupivacaine: 0.5 percentage Levobupivacaine, 24 ml used as the local anesthetic drug for supraclavicular brachial plexus block. Total volume adjusted to 25 ml in both the groups. Co

Sponsors

Swami Dayanand Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Physical Status I and II BMI less than 25 kilogram/metre square Patients scheduled for elective upper limb surgery under supraclavicular block

Exclusion criteria

Exclusion criteria: Hypersensitivity to study drugs, Prior nerve deformity or brachial plexus injury, known coagulopathy, known liver or kidney disease, known cardiorespiratory diseases, patient with opposite side pneumothorax or collapsed lung, patient scheduled for bilateral upper limb surgeries.

Design outcomes

Primary

MeasureTime frame
what will be the duration of sensory and motor blockade when dexmedetomidine or buprenorphine is used as an adjuvant to levobupivacaine in sulraclavicular brachial plexus blockTimepoint: At the time of onset of block and after surgery at the interval of 6th, 12th and 24th hours, when the block will regress to 0.

Secondary

MeasureTime frame
To compare the onset of sensory & motor blockade. To assess the sedation score using Ramsay Sedation Score. To evaluate postoperative pain & time of Rescue Analgesia using Visual Analog Scale. To assess the hemodynamics & side effects, in both groups. To assess the Patient Satisfaction Score.Timepoint: To compare the onset of sensory & motor block- At the time of onset of block & after surgery, at interval of 6th, 12th & 24hours when the block regressed to 0. Ramsay Sedation Score assessed on 30 minutes then 60, 90,120,240, 360 & at 480 minutes. Visual Analog Scale at 2 hours, then at 4, 6, 8, 10, 12, 18 & then 24 hours. Hemodynamic monitoring at 0 minute, then at 10, 20, 30, 45, 60, 75, 90 & 120 minutes. Patient Satisfaction score is measured postoperatively.;To compare the onset of sensory & motor blockadeTimepoint: At the time of onset of block & after surgery, at interval of 6th, 12th & 24 hours when the block regressed to 0.

Countries

India

Contacts

Public ContactAashish Dang

SWAMI DAYANAND HOSPITAL

drdangi679@gmail.com9810710458

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026