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Does intravenous dexamethasone decrease pain and complication rates in patients undergoing total knee replacement surgery?

The effect of intravenous dexamethasone on postoperative pain management in patients undergoing unilateral total knee arthroplasty under subarachnoid block - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/102084
Enrollment
60
Registered
2026-01-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intravenous dexamethasone 0.1mg/kg: 2 doses of 0.1 mg/kg of intravenous dexamethosone bolus given over 10 seconds, perioperatively to patients undergoing total knee arthroplasty under s

Sponsors

Dr Prem Nair
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients undergoing elective unilateral primary total knee arthroplasty.

Exclusion criteria

Exclusion criteria: Patients less than 18 years of age or more than 90 years of age uncontrolled diabetics

Design outcomes

Primary

MeasureTime frame
Decreased analgesic requirements as assessed by perioperative opioid consumptionTimepoint: Decreased analgesic requirements as assessed by perioperative opioid consumption over the first 48 hours following surgery—

Secondary

MeasureTime frame
Post-opertive nausea and vomitingTimepoint: Assessed at 48 hours postoperatively—

Countries

India

Contacts

Public ContactDr Lahari Medisetty

Amrita Institute of Medical Sciences and Research Center,Kochi

mathew.doc@gmail.com04844000514

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026