Comparison of Premixed and Sequential Intrathecal Injection Techniques Using Bupivacaine and Fentanyl for Lower Limb Surgeries

Comparison of Premixed vs Succedent Administration of Bupivacaine and Fentanyl in Subarachnoid Block for lower limb surgeries - A

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/102061

Enrollment

150

Registered

2026-01-27

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Succedent Administration Of Bupivacaine And Fentanyl: In Two Separate Syringes Bupivacaine(Heavy) 3 ml (15mg) IV

Eligibility

Inclusion criteria

Inclusion criteria: Patients Willing To Give Informed Consent Age Between 18 to 60 Years ASA Grade I And II Patients Scheduled For Elective Lower Limb Surgeries Under Subarachnoid Block

Exclusion criteria

Exclusion criteria: Patients Not Willing To Give Informed Consent ASA Grade III and IV Patients With Abnormal Coagulation Profile Patients With History Of Opioid Abuse Patients With Local Site Infections Obstetric Patients Patients With Extreme Age Group Of Less Than 18 And More Than 60

Design outcomes

Primary

Measure	Time frame
To Observe Record And Compare The Onset And Duration Of Sensory And Motor Blockade in Groups Of Patients Receiving Premixed And Succedent Administration Of Bupivacaine And Fentanyl In Subarachnoid BlockTimepoint: baseline to 300 mins	—

Secondary

Measure	Time frame
To Observe, Record And Compare The Hemodynamic Parameter In Two Groups Of Patients Receiving Premixed And Succedent Administartion Of Bupivacaine And Fentanyl In Subarachnoid BlockTimepoint: Baseline to 300 mins	—

Countries

India

Contacts

Public ContactAditya Tiwari

Peoples College of Medical Sciences And Research Centre Bhanpur Bhopal

jainabhilekh@rediff.com08571877097

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026