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A Comparison of Regional Nerve Block and Morphine for Postoperative Pain Relief Following Breast Cancer Surgery

COMPARISION OF POST-OPERATIVE ANALGESIA USING ULTRASOUND GUIDED ERECTOR SPINAE PLANE BLOCK VERSUS INTRAVENOUS MORPHINE AND LOCAL ANAESTHETIC WOUND INFILTRATION IN PATIENTS UNDERGOING MODIFIED RADICAL MASTECTOMY - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/102049
Enrollment
64
Registered
2026-01-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site Health Condition 2: C504- Malignant neoplasm of upper-outerquadrant of breast

Interventions

Intervention1: COMPARISION OF POST-OPERATIVE ANALGESIA USING ULTRASOUND GUIDED ERECTOR SPINAE PLANE BLOCK VERSUS INTRAVENOUS MORPHINE FOLLOWED BY LOCAL ANAESTHETIC WOUND INFILTRATION IN PATIENTS UNDER

Sponsors

Vardhman Mahavir Medical College and Safdarjung hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult female patients aged between 18-65 years with ASA(American Society of Anaesthesiologists) grade between I-III who are posted for elective modified radical mastectomy under general anaesthesia are included.

Exclusion criteria

Exclusion criteria: The patients with the following preoperative conditions will be excluded from the study: 1. Contraindication to nerve block(coagulopathies/on anticoagulants/ local site infection) 2. Patients who will be known cases of CKD, and COPD. 3. Pregnancy 4. Patients with spinal anomalies. 5. Drug allergy. 6. Patients who have cognitive disability and are unable to understand the NRS score.

Design outcomes

Primary

MeasureTime frame
To compare the post-operative analgesic efficacy of ultrasound guided erector spinae block with intraoperative intravenous morphine followed by local anaesthetic infiltration at the incision site in patients undergoing modified radical mastectomy using Numerical Rating Scale(NRS) at 4 hours.Timepoint: 4 hours.—

Secondary

MeasureTime frame
1. To compare the amount of additional analgesia required over 24 hours in both groups. 2. To compare postoperative analgesia duration(time to first rescue analgesia) in first 24 hours in both groups.Timepoint: 24 hours—

Countries

India

Contacts

Public ContactDrNishtha Kachru

Vardhman Mahavir Medical College and Safdarjung hospital

kachnishtha98@gmail.com9958844229

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026