Health Condition 1: H401- Open-angle glaucoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosis of primary angle glaucoma as per the Consulting Ophthalmologist. Best-corrected visual acuity (BCVA) of more than or equal to 6/18 in the better eye on Snellen visual acuity chart 45 to 80 years of age At least 5 years of formal education Conversant in Kannada or English Willing to participate and provide written informed consent
Exclusion criteria
Exclusion criteria: Exclusion Criteria Diagnosis of Depression as per Geriatric Depression Scale (GDS)- SF Clinically diagnosed Psychiatric illness/subnormal mentation/ Intellectual and Developmental Disabilities Comorbid neurological disorders that may make neurocognitive assessment challenging. Severe hearing impairment that precludes effective participation in neurocognitive assessment Patient unwilling to take part in the study Ophthalmic exclusion criteria Glaucoma other than POAG - Primary angle closure glaucoma, secondary glaucoma Eye disease that could have affected RNFL and GCL thickness, such as macular degeneration and optic neuropathy Diseases causing visual field defects - Retinitis Pigmentosa, Retinal Detachment, Central Serous Retinopathy, Age-related Macular Degeneration (AMD), Diabetic Retinopathy, Hypertensive Retinopathy Patients on medications causing visual field defects - Chloroquine, Hydroxychloroquine, Thioridazine, Tamoxifen, Vigabatrin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PRIMARY OBJECTIVES: To assess the neurocognitive functioning in patients diagnosed with POAG using standardized cognitive screening tools. To evaluate the quality of life (QoL) in patients with POAG using disease-specific QoL questionnaires. To examine the level of functional impairment in daily living activities among POAG patients. Timepoint: At the time of first contact with patient. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life, and functioningTimepoint: ;To identify potential predictors (clinical, ophthalmological, psychiatric or medical) of cognitive impairment & functional decline in this population. To explore associations between the severity of POAG & Neurocognitive performance, Quality of life, & Functional status. Timepoint: At the time of analysis of results. | — |
Countries
India
Contacts
Kasturba Medical College, Manipal, Manipal Academy of Higher Education