Skip to content

A study to understand brain functioning and Quality of life in Glaucoma patients.

Neurocognitive profile, Quality of life, and Functioning in patients with Primary Open Angle Glaucoma A hospital based Cross sectional Exploratory study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/01/102044
Enrollment
30
Registered
2026-01-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H401- Open-angle glaucoma

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

PG RESEARCH FUND KMC
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Diagnosis of primary angle glaucoma as per the Consulting Ophthalmologist. Best-corrected visual acuity (BCVA) of more than or equal to 6/18 in the better eye on Snellen visual acuity chart 45 to 80 years of age At least 5 years of formal education Conversant in Kannada or English Willing to participate and provide written informed consent

Exclusion criteria

Exclusion criteria: Exclusion Criteria Diagnosis of Depression as per Geriatric Depression Scale (GDS)- SF Clinically diagnosed Psychiatric illness/subnormal mentation/ Intellectual and Developmental Disabilities Comorbid neurological disorders that may make neurocognitive assessment challenging. Severe hearing impairment that precludes effective participation in neurocognitive assessment Patient unwilling to take part in the study Ophthalmic exclusion criteria Glaucoma other than POAG - Primary angle closure glaucoma, secondary glaucoma Eye disease that could have affected RNFL and GCL thickness, such as macular degeneration and optic neuropathy Diseases causing visual field defects - Retinitis Pigmentosa, Retinal Detachment, Central Serous Retinopathy, Age-related Macular Degeneration (AMD), Diabetic Retinopathy, Hypertensive Retinopathy Patients on medications causing visual field defects - Chloroquine, Hydroxychloroquine, Thioridazine, Tamoxifen, Vigabatrin

Design outcomes

Primary

MeasureTime frame
PRIMARY OBJECTIVES: To assess the neurocognitive functioning in patients diagnosed with POAG using standardized cognitive screening tools. To evaluate the quality of life (QoL) in patients with POAG using disease-specific QoL questionnaires. To examine the level of functional impairment in daily living activities among POAG patients. Timepoint: At the time of first contact with patient.

Secondary

MeasureTime frame
Quality of life, and functioningTimepoint: ;To identify potential predictors (clinical, ophthalmological, psychiatric or medical) of cognitive impairment & functional decline in this population. To explore associations between the severity of POAG & Neurocognitive performance, Quality of life, & Functional status. Timepoint: At the time of analysis of results.

Countries

India

Contacts

Public ContactDr Suma Udupa

Kasturba Medical College, Manipal, Manipal Academy of Higher Education

udupa.suma@manipal.edu9901790003

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026