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Comparing heart ultrasound findings before and after surgery to measure muscle strain and predict complications in elective off-pump bypass surgery patients.

Perioperative evaluation of transthoracic echocardiography derived left atrial strain using speckle-tracking: its correlation with transesophageal echocardiography derived diastolic dysfunction and postoperative adverse outcomes in elective off-pump coronary artery bypass graft surgery. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/01/102031
Enrollment
40
Registered
2026-01-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery

Interventions

Intervention1: Nil: Nil

Sponsors

Govind Ballabh Pant Institute of Postgraduate Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients scheduled for elective isolated off-pump coronary artery bypass graft (CABG) surgery. Sinus rhythm on preoperative electrocardiogram. Adequate transthoracic echocardiographic windows for strain analysis. Written informed consent.

Exclusion criteria

Exclusion criteria: On-pump CABG surgery. Combined valve and off-pump CABG surgery. Previous cardiac surgery. Severe mitral or aortic valve disease (moderate-severe or severe). Congenital heart disease. Severe left ventricular dysfunction (Ejection fraction less than 30 percent). Severe pulmonary hypertension (Pulmonary Artery Systolic Pressure more than 60 mmHg). Severe renal dysfunction. (eGFR less than 30ml/min/1.73m2) Poor echocardiographic image quality precluding strain analysis.

Design outcomes

Primary

MeasureTime frame
Mean percentage change in left atrial strain parameters from preoperative baseline to postoperative day 7 2.Timepoint: Baseline (T0) and Postoperative Day 7 2 (T2).—

Secondary

MeasureTime frame
Relationship between preoperative LA strain parameters and preoperative TEE-based diastolic dysfunction grading.Timepoint: Baseline (T0) and Postoperative Day 7 2 (T2).;Incidence of postoperative atrial fibrillation (POAF).Timepoint: Baseline (T0) and Postoperative Day 7 2 (T2).;Incidence of low cardiac output syndrome (LCOS) requiring inotropic support.Timepoint: Baseline (T0) and Postoperative Day 7 2 (T2).;Incidence of acute kidney injury (AKI) stratified by KDIGO stage.Timepoint: Baseline (T0) and Postoperative Day 7 2 (T2).;Incidence of prolonged mechanical ventilation, defined as requirement exceeding 24 hours.Timepoint: Baseline (T0) and Postoperative Day 7 2 (T2).;30-day in-hospital mortality rate.Timepoint: 30 days following the surgical procedure.—

Countries

India

Contacts

Public ContactDr Sanjula Virmani

Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, New Delhi

drsanjulavirmani@yahoo.co.in9718599409

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026