A clinical trial to study the Efficacy of Low-Level Light Therapy on improving Depressive Symptoms in patients with Major Depressive Disorder.

Efficacy of Transcranial Low-Level Light Therapy on Executive Function and Depressive Symptoms in patients with Major Depressive Disorder. - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/102027

Enrollment

Registered

2026-01-27

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F339- Major depressive disorder, recurrent, unspecified

Interventions

Intervention1: Transcranial Low-Level Light Therapy in patients with Major Depressive Disorder having SOC (standard of care).: Administer Low-Level Light of 4 W Power and wavelength of 1064 nm over bi

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18-65 years diagnosed with Major Depressive Disorder.

Exclusion criteria

Exclusion criteria: 1.Hemodynamically unstable patients. 2.History of sensitivity to light. 3.Patients with a history of seizure/epilepsy or stroke. 4.Currently pregnant. 5.Smokers. 6.Diabetics. 7.Patients with active suicidal behaviour. 8.Violent behaviour.

Design outcomes

Primary

Measure	Time frame
Improvement in executive function and depressive symptomsTimepoint: The outcome will be assessed at baseline, at 1 week, at 2 week and at 6 week.	—

Secondary

Measure	Time frame
To assess the change in executive function and depressive symptoms after 4 weeks of follow up from last LLLT.Timepoint: 4 weeks of follow up	—

Countries

India

Contacts

Public ContactDr Dilip Kumar

AIIMS Patna

drdkmobile@gmail.com9555409501

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026