Health Condition 1: C269- Malignant neoplasm of ill-definedsites within the digestive system
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Personalized Prebiotics: Leveraging the microbiome by studying microbial patterns and subsequently personalising prebiotics (nutritional
Sponsors
Cachar Cancer Hospital & Research Centre (CCHRC).
Iom Bioworks Pvt Ltd
Eligibility
Inclusion criteria
Inclusion criteria: Condition: Diagnosed with Upper GI cancer (for patient group). BMI: 18 29.9 kg/m . Other: Willingness to provide stool samples and provide informed consent.
Exclusion criteria
Exclusion criteria: Chronic illnesses requiring hospitalization or known GI disorders. Major surgery/hospitalization in the last 6 months. Long-term antibiotic/anti-tubercular treatment. COVID-19 infection within the last 3 months. Intolerance to prebiotic ingredients (for the interventional phase).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in gut microbiota composition and identification of bacterial signatures associated with cancer treatment.Timepoint: Baseline (Day 1), Post-treatment (Day 60), Follow-up (Day 90 150) | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in microbial diversity, correlation with clinical and demographic variables, and patient-reported wellness outcomes (sleep, fatigue, stress).Timepoint: Baseline, 8 weeks post-intervention. | — |
Countries
India
Contacts
Public ContactDr Rajeev Kumar
Cachar Cancer Hospital and Research Centre
Outcome results
None listed