A Clinical Study to see the Impact of MA2/24 and Caffeine vs. Placebo on Mental and Physical Stamina

A Prospective, Randomized, Double-blind, Cross-Over, Placebo-controlled Study to Evaluate the Impact of MA2/24 and Caffeine (Alone or in Combination) vs. Placebo on Mental and Physical Stamina - Nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/101999

Enrollment

Registered

2026-01-23

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: MA2/24: One sachet in 200ml water once in a day for 7 days Intervention2: MA2/24 + Caffeine: One sachet in 200ml water once in a day for 7 days Intervention3: Caffeine: One sachet in

Eligibility

Inclusion criteria

Inclusion criteria: 1.Healthy adults who consume less than 200 mg caffeine per day 2.Employed or performing regular daytime work greater than or equal to 5days per week and greater than or equal to 8hours per day 3.Self-report of feeling tired by the evening on most working days (greater than or equal to 4days per week) confirmed by screening questions and by validated Fatigue Severity Scale (FSS) and ESS. 4.Willing and able to attend clinic visits in the assessment window. 5.BMI 18.5 30 kg per meter square. 6.Willingness to refrain from medications, alcohol or supplements 12 hours prior to testing. 7.Ability to provide informed consent and comply with all study requirements.

Exclusion criteria

Exclusion criteria: 1.Pregnant or lactating women 2.Individuals with cardiovascular disease, hypertension, metabolic disorders, current diagnosis of major psychiatric disorder or cognitive disorder, chronic fatigue syndrome or post-viral fatigue diagnosis 3.Individuals with hearing or visual impairment, sleep disorders, or shift workers 4.Individuals with excessive daytime sleepiness 5.Hypersensitivity to study products 6.Chronic caffeine consumers exceeding 400 mg per day 7.Use of medications and supplements that could affect cognitive or physical performance 8.Chronic medical conditions or lifestyle factors that may affect outcomes. 9.Participation in another clinical trial within the past 30 days. 10.Prior experience or familiarity with the assessment tool.

Design outcomes

Primary

Measure	Time frame
Effect of MA2/24 supplementation on physical and mental stamina, endurance and cognitive functionsTimepoint: Baseline and Day 7	—

Secondary

Measure	Time frame
Effect of MA2/24 in fatigue, daytime sleepinessTimepoint: Baseline and Day 7;Overall safetyTimepoint: Baseline and EOS	—

Countries

India

Contacts

Public ContactJestin V Thomas

Leads Clinical Research and Bio Services Pvt. Ltd.

jestin.leadsclinbio@gmail.com9845125293

Outcome results