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Comparison of the efficacy and safety of 2 modalities for the treatment of striae distensae-Combined Fractional CO2 laser and topical Poly-L Lactic acid Gel versus Fractional CO2

Study of the efficacy and saftey of combined fractional co2 laser and topical poly-l lactic acid gel versus fractional co2 laser in the the treatment of striae distensae : a randomized controlled trial - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/101915
Enrollment
60
Registered
2026-01-23
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L99- Other disorders of skin and subcutaneous tissue in diseases classified elsewhere

Interventions

Intervention1: Fractional Carbon Dioxide Laser: 4 weeks for a total of 3 treatment sessions. Intervention2: Fractional CO2 with Topical Poly-L_ lactic acid gel: an interval of of 4 weeks for a total

Sponsors

Dr Kenkre Namrata Sandeep
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of both genders with striae distensae of all grades present over any part of the body. 2. Patients who have not taken treatment for striae distensae either topical or systemic in the past 6 months

Exclusion criteria

Exclusion criteria: 1. Patients on topical retinoids or systemic corticosteroids. 2. Patients with history of keloid formation. 3. Patients with any connective tissue disease. 4. Patients with disease affecting the wound-healing process. 5. Patients with other systemic illness bleeding disorders , cardiac, renal, hepatic illness. 6. Pregnancy, Lactation

Design outcomes

Primary

MeasureTime frame
To assess and compare the efficacy of Fractional CO2 Laser and Poly-l-lactic acid (PLLA) Gel versus Fractional CO2 Laser in the treatment of Striae DistensaeTimepoint: at an interval of 4 weeks for a total of 3 treatment sessions.

Secondary

MeasureTime frame
To identify the post procedural adverse effects of Fractional CO2 Laser and Poly-l-lactic acid (PLLA) Gel versus Fractional CO2 Laser in the treatment of Striae DistensaeTimepoint: at an interval of 4 weeks for a total of 3 treatment sessions.

Countries

India

Contacts

Public ContactDr Rajashekar T S

R L Jalappa Hospital

rajashekardermat@sduaher.ac.in9448316136

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026