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COMPARISON OF THE EFFECT OF PERIOPERATIVE INTRAVENOUS INFUSION OF DEXMEDETOMIDINE AND LIGNOCAINE VERSUS FENTANYL ON INTRAOPERATIVE HAEMODYNAMICS AND POSTOPERATIVE ANALGESIA IN ELECTIVE LAPAROSCOPIC SURGERY

COMPARISON OF THE EFFECT OF PERIOPERATIVE INTRAVENOUS INFUSION OF DEXMEDETOMIDINE AND LIGNOCAINE VERSUS FENTANYL ON INTRAOPERATIVE HAEMODYNAMICS AND POSTOPERATIVE ANALGESIA IN ELECTIVE LAPAROSCOPIC SURGERY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/101899
Enrollment
200
Registered
2026-01-23
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K839- Disease of biliary tract, unspecified

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Air Force Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adults age 18 65 years. ASA physical status I II (or III if you prefer). Scheduled for elective laparoscopic procedures under general anesthesia with expected duration 60 180 minutes. Able to provide informed consent.

Exclusion criteria

Exclusion criteria: Known allergy to study drugs (dexmedetomidine, lignocaine, fentanyl). Severe cardiac conduction disease (2nd or 3rd degree heart block without pacemaker). Significant hepatic dysfunction, severe renal impairment. Pregnancy or breastfeeding. Chronic opioid use or chronic pain requiring opioids. BMI more than 35 Severe psychiatric disease or inability to report pain scores. Seizure disorder relative contraindication to lignocaine infusion

Design outcomes

Primary

MeasureTime frame
To compare intraoperative haemodynamic effect between Dexmedetomidine and Lignocaine group with Fentanyl group during elective laparoscopic surgeries and postoperative analgesia in both the groups. Further to achieve the goal of opioid free anaesthesiaTimepoint: To compare intraoperative haemodynamic effect between Dexmedetomidine and Lignocaine group with Fentanyl group during elective laparoscopic surgeries and postoperative analgesia in both the groups. Further to achieve the goal of opioid free anaesthesia—

Secondary

MeasureTime frame
Compare postoperative pain scores (VAS/NRS) at rest at 0, 1, 2, 6, 12, 24 hours. Total postoperative opioid consumption in the first 24 hours. Time to first analgesic request. Incidence of PONV, sedation scores, respiratory depression, and other adverse events. Time to extubation / PACU stay length and overall recovery profile (where applicable). Timepoint:—

Countries

India

Contacts

Public ContactDr Shaik Nagoor Vali

7 Air Force Hospital

drbhaskar23@gmail.com7507088990

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026