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To study the effect of adding Dexmedetomidine to Total Intravenous Anaesthesia on the Quality of Recovery of patients undergoing Thyroid Surgery.

Effect of Dexmedetomidine as an Adjunct to Total Intravenous Anaesthesia on the Quality of Recovery in patients undergoing Thyroid Surgery with Intraoperative Nerve Monitoring - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/101883
Enrollment
80
Registered
2026-01-23
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C73- Malignant neoplasm of thyroid gland

Interventions

Intervention1: Dexmedetomidine: Dexmedetomidine group patients will receive continuous infusion of 0.4 g/kg/hr starting at induction of anaesthesia and will be stopped 1 hour before the anticipated e

Sponsors

All India Institute of Medical Sciences AIIMS New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA Physical status 1-2 2.Scheduled for thyroid surgeries with intraoperative nerve monitoring 3.Ability to understand and complete QoR40 questionnaire 4.Signed informed consent

Exclusion criteria

Exclusion criteria: 1. Pre-existing vocal cord dysfunction 2. ASAPhysical status 3-4 3. known allergy to propofol, fentanyl, dexmedetomidine 4. pre-existing cardiac conditions 5. morbid obesity 6. refusal to consent

Design outcomes

Primary

MeasureTime frame
Quality of Recovery using QoR-40 questionnaire score in patients undergoing thyroid surgery with Intraoperative NeuromonitoringTimepoint: 24 hours after surgery (on postoperative day 1)—

Secondary

MeasureTime frame
To determine the total intraoperative Propofol & Fentanyl consumption between the two groups.Timepoint: at extubation;To determine the time to eye opening or verbal response after discontinuation of anaesthetic agents.Timepoint: at end of surgery;To determine the Sedation Score using Ramsay Sedation Scale at 30 minutes & 60 minutes in the Post-Anaesthesia Care Unit (PACU).Timepoint: 30 minutes & 60 mins after arrival in PACU;To determine the haemodynamic parameters as Heart Rate (HR) & Mean Arterial Pressure (MAP) at 1, 3,5,10 & 15 minutes post-intubation, every 15 minutes intraoperatively, & at extubation.Timepoint: Baseline(pre induction) 1,3,5,10,15 mins post intubation, every 15 minutes in intraoperative period, at extubation—

Countries

India

Contacts

Public ContactDr Brajesh Kumar Ratre

AIIMS, New Delhi

brajesh.ratre@gmail.com8696156799

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026