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Use of Artificial intelligence and MRI for predicting brain tumor recurrence

Development and validation of Artificial Intelligence (AI) models for prediction of glioma and meningioma recurrence using preoperative MRI A Multicenter study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/01/101817
Enrollment
380
Registered
2026-01-22
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C719- Malignant neoplasm of brain, unspecified Health Condition 2: C700- Malignant neoplasm of cerebral meninges

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Nil: Nil Control Intervention1: Nil: Nil

Sponsors

Indian Council of Medical Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Phase I (Retrospective) Inclusion criteria: 1. Pre- and post-operative MRI Brain Images of the patients diagnosed with meningioma / Gliomas Phase II (Prospective) Inclusion criteria: 1. Post operative cases referred for MRI Brain diagnosed with meningioma / Gliomas with available preoperative images

Exclusion criteria

Exclusion criteria: Phase I (Retrospective) Exclusion criteria: 1. Patients who had incomplete MRI Brain imaging data 2. Suboptimal MRI image quality Phase II (Prospective) Exclusion criteria: 1. Suboptimal MRI image quality

Design outcomes

Primary

MeasureTime frame
Phase I: The accuracy of Machine Learning (ML) and Deep Learning (DL) models for predicting glioma and meningioma recurrence using preoperative MRI with combined clinical and radiomic features. Phase II: Validation of the developed models Development of explainable AI modelsTimepoint: Phase I: (Retrospective) 1. Preoperative MRI scan 2. Post Operative MRI scan to check for the recurrence status Phase II: 1. Preoperative MRI 2. Post Operative MRI scan to check for the recurrence status

Secondary

MeasureTime frame
Radiomic characterization of tumorsTimepoint: 1. Preoperative MRI Scan

Countries

India

Contacts

Public ContactDr Rajagopal Kadavigere Venkatachalaiah

Manipal Academy of Higher Education

rajarad@gmail.com9448158901

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026