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Effect of Topical Tranexamic Acid compared to Normal saline on Bleeding during Tonsillectomy surgery

Hemostatic efficacy of Topical Tranexamic acid versus Normal saline During Tonsillectomy Surgery-A double blinded Randomized Controlled trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/101719
Enrollment
50
Registered
2026-01-21
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Topical Tranexamic Acid: Tranexamic acid solution soaked gauze packs placed over tonsillar fossa immediately after tonsillectomy for 5 Minutes. Control Intervention1: Normal Saline: Nor

Sponsors

Bandla Bharath Chandra
Lead Sponsor
Aarupadai Veedu Medical College and Hospital
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients scheduled for Elective tonsillectomy Age group 5-60 years Informed consent obtained from patient or legal gaurdian ASA physical status 1 and 2

Exclusion criteria

Exclusion criteria: Known hypersensitivity to Tranexamic acid Pregnant and breast feeding women Patient not willing to give consent IF any coagulation disorders IF any comorbidities or malignancies

Design outcomes

Primary

MeasureTime frame
Intra operative Blood loss measured in millilitres using surgical suction and gauze weight differenceTimepoint: Blood loss measurement will start from the time of tonsillar tissue removal upto completion of the surgery gauze weight will be measured from post tonsillar tissue removal upto completion of surgery.

Secondary

MeasureTime frame
Operative time periodTimepoint: Intra operative period will be calculated from mucosal incision to completion of tonsillectomy;Duration of hospital stay compared between intervention & control groupsTimepoint: Postoperative period will be calculated from completion of surgery until time of hospital discharge

Countries

India

Contacts

Public ContactBandla Bharath Chandra

Aarupadai Veedu Medical College and Hospital

docnishuu@gmail.com9894547810

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026