Treatment of intraosseous Vertical periodontal defect using NOVO graft as a bone regenerative material in patients having chronic generalized periodontitis with periodontal pockets of more than or equals to 5 mm

To evaluate the efficacy of NOVO graft as a bone regenerative material in the treatment of intraosseous periodontal defects: A clinical and CBCT analysis - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/101553

Enrollment

Registered

2026-01-19

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

Intervention1: NOVO Graft: open flap debridement with placement of NOVO GRAFT in intra osseous periodontal defects Control Intervention1: Without NOVO Graft: open flap debridement alone in intraosseo

Eligibility

Inclusion criteria

Inclusion criteria: (1)Patients diagnosed as having chronic generalized periodontitis with periodontal pockets of more than or equal to 5 mm with radiographic evidence of vertical bone loss (2 walled and 3 walled defects) (2)Age group between 30 to 55 years (3)Patients with good general health without any history of systemic disease or medication.

Exclusion criteria

Exclusion criteria: (1)Patients showing unacceptable oral hygiene during pre surgical (Phase I) period (2)Smokers (3)pregnant women and lactating mothers

Design outcomes

Primary

Measure	Time frame
Increase in the amount of bone fill in the periodontal 2 walled and 3 walled intraosseous defectsTimepoint: Baseline, 3 months, 6 months, 9 months	—

Secondary

Measure	Time frame
Decrease in probing pocket depth and increase in relative attachment level before and after treatmentTimepoint: Baseline, 3 months, 6 months, 9 months	—

Countries

India

Contacts

Public ContactDr Shalini Mishra

Hitkarini Dental College and Hospital

elashree03@gmail.com7000395785

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026