Health Condition 1: Z418- Encounter for other procedures forpurposes other than remedying health state
Conditions
Interventions
Intervention1: Dexmeditomedine: Intravenous Dexmedetomidine 0.7 microgram per kilogram body weight diluted in 20 ml normal saline and administered as infusion over 10 minutes completed before inductio
Sponsors
Pacific medical college and hospital
Eligibility
Inclusion criteria
Inclusion criteria: Patients of either sex posted for elective surgeries under general anesthesia requiring endotracheal intubation ASA Grade I and II
Exclusion criteria
Exclusion criteria: Drug allergy to the study drugs Patients with anticipated difficult airway Laryngoscopy time more than 20 secs Patients with a history of chronic hypertension diabetes hepatic disease or renal disease or on preoperative beta blockers and pregnant or lactating women coexisting cardiorespiratory disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in mean arterial pressure MAP following laryngoscopy and endotracheal intubationTimepoint: Mean arterial pressure assessed at baseline during laryngoscopy immediately after intubation and 5 minutes postintubation | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate systolic blood pressure diastolic blood pressure mean arterial pressure & incidence of adverse events bradycardia hypotension following administration of study drugs during laryngoscopy & endotracheal intubationTimepoint: Heart rate systolic & diastolic blood pressure assessed at baseline during laryngoscopy immediately after intubation & 5 minutes postintubation Incidence of adverse effects bradycardia hypotension during the periintubation period | — |
Countries
India
Contacts
Public ContactDr Vijay Kumar
Pacific Medical College and Hospital
Outcome results
None listed