Health Condition 1: R098- Other specified symptoms and signsinvolving the circulatory and respiratory systems Health Condition 2: J22- Unspecified acute lower respiratory infection
Conditions
Interventions
Intervention1: Vitamin B12 and vitamin D supplementation.
: Participants in this group will receive cobalamin (vitamin B12) 1000 mcg intravenously once daily from day 1 to day 7, along with vitamin D
Sponsors
All India Institute of Medical Sciences Jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged twenty five to seventy five years admitted to the ICU. Patients with a Glasgow Coma Scale score of eight or above and a Richmond Agitation Sedation Scale score minus three or above. Patients are expected to stay in the ICU for at least forty eight hours.
Exclusion criteria
Exclusion criteria: Patients refused to participate in the study. Patients aged below twenty five years or above seventy five years. Patients with a Glasgow Coma Scale score below eight or a Richmond Agitation Sedation Scale score below minus three. Patients with traumatic brain injury. Patients with severe septic shock and multi-organ dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of delirium in patients recieving vitamin b12 and vitamin D during ICU stay. Timepoint: Baseline assessment within 24 hours of ICU admission, followed by daily assessment during ICU stay until ICU discharge. | — |
Secondary
| Measure | Time frame |
|---|---|
| TO assess 1.Serum levels of vitamin B12 & vitamin D. 2.Duration of ICU stay. 3.Number of delirium free days during ICU stay. 4.Cognitive function at ICU discharge. 5.Quality of life at hospital discharge. Timepoint: Baseline assessment within 24 hours of ICU admission, followed by daily assessment during ICU stay until ICU discharge. | — |
Countries
India
Contacts
Public ContactChethan V
All India Institute of Medical Sciences, Jodhpur
Outcome results
None listed