Comparison of incidence of postoperative nausea and vomiting between sugammadex and neostigmine in patients undergoing laparoscopic cholecystectomy

Comparison of sugammadex and neostigmine administration on the incidence of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy- a randomised clinical trial - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/101476

Enrollment

110

Registered

2026-01-19

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis Health Condition 2: K802- Calculus of gallbladder without cholecystitis Health Condition 3: O- Medical and Surgical Health Condition 4: K811- Chronic cholecystitis

Interventions

Intervention1: Sugammadex 2mg/ml: Study participants will be randomized into two groups. Intervention group will receive sugammadex 2mg/kg before extubation.Total duration of procedure from intubation

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 to 60 years of either gender- male or female. 2. Patients with American Soceity of Anesthesia(ASA) physical status grade 1 to grade 2

Exclusion criteria

Exclusion criteria: 1. Repeat surgery within 24 hrs after Anesthesia. 2. Lack of consciousness after surgery. 3. Ventilator therapy after Anesthesia. 4. Nausea or vomiting before Anesthesia. 5. History of smoking.

Design outcomes

Primary

Measure	Time frame
To compare the incidence of post-operative nausea and vomiting of sugammadex and neostigmine in patients undergoing laparoscopic cholecystectomy.Timepoint: Time to nausea . Time to vomiting. Time for need for rescue anti-emetic.	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactRupendra Singh thokchom

Regional institute of medical science ,Imphal,Manipur

Penbeeru63@gmail.com9774247043

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026