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A study comparing effects of muscle relaxants on kidney transplant function

Comparison of rocuronium-sugammadex vs cis-atracurium-neostigmine during kidney transplantation on the recovery of graft function evaluated in terms of serum creatinine at 24 hours: A Randomised controlled trial - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/101441
Enrollment
84
Registered
2026-01-19
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N186- End stage renal disease Health Condition 2: N186- End stage renal disease

Interventions

Intervention1: rocuronium-sugammadex group: Group 1: Rocuronium at a dose of 0.6 mg/kg will be administered for induction, IV, at the time of induction with maintenance dose 0.1-0.2 mg/kg rocuronium.

Sponsors

PGIMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patient 18 to 65 Year Living donor renal transplant

Exclusion criteria

Exclusion criteria: Age less than 18 years Allergies to any drug used Anticipated difficult airway

Design outcomes

Primary

MeasureTime frame
To compare the impact of rocuronium-sugammadex vs cisatracurium-neostigmine during kidney transplantation on the recovery of graft function, evaluated in terms of serum creatinine at 24 hoursTimepoint: in 24 hours

Secondary

MeasureTime frame
serum creatinine serum urea and serum electrolyte diuresis and urinary sodium and potassium need for dialysisTimepoint: in 6,12,48,72 hours

Countries

India

Contacts

Public ContactDR SHALINI

PGIMER CHANDIGARH

sameersethi29@gmail.com9317851002

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026