Comparison of Lignocaine with & without Magnesium Sulphate for Infraorbital Nerve Block in Upper premolar extraction

Comparative evaluation of effectiveness of 2 percent lignocaine HCl, 2 percent lignocaine HCl with 0.2 ml 10 percent magnesium sulfate and 2 percent lignocaine HCl with 1:200,000 adrenaline 0.2 ml 10 percent magnesium sulfate in infraorbital nerve block- a randomized controlled trial - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/01/101407

Enrollment

Registered

2026-01-16

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K089- Disorder of teeth and supporting structures, unspecified

Interventions

Intervention1: Lignocaine with Adrenaline with Magnesium Sulphate: 2 percent lignocaine HCl with adrenaline 1 is to 200000 plus 0 point 2 ml 10 percent magnesium sulfate in Infraorbital Nerve block du

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patients above 18 years of age 2 Patients reporting to the department of Oral and Maxillofacial Surgery for extraction of Maxillary premolar

Exclusion criteria

Exclusion criteria: 1 Patients allergic to Local Anesthesia 2 Patients not willing to give informed consent

Design outcomes

Primary

Measure	Time frame
Assessment of action of anesthesia, duration of action of anaesthesia and pain during procedureTimepoint: Onset of action of anesthesia duration of action of anaesthesia and pain during procedure will be assessed on the same day during procedure	—

Secondary

Measure	Time frame
Assessment of pulse rate, systolic & diastolic blood pressureTimepoint: assessment of pulse rate, systolic & diastolic blood pressure before administration of anaesthesia i.e baseline & during procedure	—

Countries

India

Contacts

Public ContactDr Ramakrishna Shenoi

Ranjeet Deshmukh Dental College and Research Centre Nagpur

ramakrishna.shenoi@gmail.com9822220505

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026