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Comparative Clinical Trial of 2% Curcumin Gel, 99% Aloe Vera Gel, and 1% Chlorhexidine Gel in Treating Stage II Grade B Periodontitis

Comparative evaluation of clinical efficacy of 2 percent curcumin gel 99 percent aloevera extract gel and 1 percent chlorhexidine gel as local drug delivery in Stage II Grade B periodontitis patients A Single blind randomized controlled clinical trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/101396
Enrollment
45
Registered
2026-01-16
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: 2% curcumin gel, 99% aloevera extract gel: Natural ingredients used to treat stage II grade B periodontitis Control Intervention1: 1.0% Chlorhexidine gel: Gold standard ingredient used

Sponsors

Dr Namrata Diliprao Adhau
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients within age group of 18- 45 years with Stage II Grade B periodontitis. 2. Patients with residual probing pocket depth of 3-4 mm after 4 weeks of scaling and root planing will be selected for the study. 3. Patients who have not undergone any periodontal therapy 6 months before the initial examination.

Exclusion criteria

Exclusion criteria: 1. Smokers and tobacco chewer. 2. Patients on antibiotics one month prior to treatment. 3. Patients using orthodontic or prosthodontic appliances either fixed or removable. 4. Patients who have used oral gels or mouthwash containing chemical agents in previous two months. 5. Patients allergic or sensitive to any medication present in the administered gel. 6. Patients with chronic diseases such as Diabetes mellitus, arthritis, thyroid disorder, etc. 7. Female patients who are pregnant or lactating.

Design outcomes

Primary

MeasureTime frame
To compare scores of plaque index(GI), gingival index(GI), Probing pocket depth (PPD) , Clinical attachment level (CAL), Modified sulcus bleeding index(mSBI) after administration of 2% curcumin gel, 99% aloevera gel and 1.0% chlorhexidine gel at 4 weeks and 8 weeks in Stage II grade B Periodontitis Patients.Timepoint: Baseline,4 weeks,8weeks—

Secondary

MeasureTime frame
N/ATimepoint: N/A—

Countries

India

Contacts

Public ContactDrNamrata Diliprao Adhau

MGVs KBH Dental College and Hospital ,Nashik

triv19792018@gmail.com8552011711

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026