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Comparison of Hemodynamic changes caused by Ropivacaine and Levobupivacaine in patients with mildly reduced heart function undergoing lower abdominal and leg surgeries under spinal anesthesia.

Ropivacaine vs Levo-bupivacaine for Subarachnoid Block in patients with mildly reduced ejection fraction undergoing lower limb and infraumbilical abdominal surgeries - No acronym

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/01/101316
Enrollment
70
Registered
2026-01-16
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Levobupivacaine: Levobupivacaine 0.5 percent, heavy, 3ml for spinal anesthesia in patients with left ventricular ejection fraction mildly reduced(41-49 percent) undergoing lover limb o

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients who will undergo elective lower limb or infraumbilical abdominal surgeries under spinal anesthesia with mildly reduced cardiac ejection fraction (41-49%). Patients in age group of 18 -70 years.

Exclusion criteria

Exclusion criteria: Those with deranged coagulation profile. Patient who having history of allergy to local anesthetics ropivacaine/ levobupivacaine. Those with diabetic autonomic neuropathy or any neurological disease of spinal cord. Those with the severe hypotension, critical valvular stenosis, Ventricular outlet obstruction etc. Patients with history of substance abuse

Design outcomes

Primary

MeasureTime frame
To compare the incidence and severity of Hemodynamic changes after giving ropivacaine and levobupivacaine for subarachnoid block and need for Vasopressor drugs between two groups.Timepoint: To compare the incidence and severity of Hemodynamic changes after giving ropivacaine or levobupivacaine for subarachnoid block and need for Vasopressor drugs between two groups at every 2min in first 20 min and every 20min till surgery completed.—

Secondary

MeasureTime frame
To compare the time onset of highest sensory segmental block up To T8-10 , duration of motor and sensory block, Quality of block (Bromage score), regression of block to L1 level, incidence of Nausea/ vomiting, shivering and time for the rescue analgesia in post operative period between the two groups.Timepoint: For time onset of block, quality of motor and sensory block we will check at every 2 min for first 30 min after giving spinal anesthesia. For duration of block and need for rescue analgesic we will check every 30 min in recovery room.—

Countries

India

Contacts

Public ContactDr Mridul Madhav Panditrao

Adesh University

sonaattri45@gmail.com9915461044

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026