Health Condition 1: L811- Chloasma
Conditions
Interventions
Intervention1: Cysteamine hydrochloride + Pycnogenol + Tranexamic Acid: Wash your face with the study face wash.
Apply cysteamine + pycnogenol serum for 15 minutes.
Wash your face again.
Apply Tranexa
Sponsors
SILPHION RESEARCH PRIVATE LIMITED
Eligibility
Inclusion criteria
Inclusion criteria: Adults aged 18-55 years of any gender or ethnicity Clinical diagnosis of melasma, not on any treatment at least for the past 4 weeks. Fitzpatrick skin types III to V Willingness to adhere to study protocol and attend follow-up visits Signed informed consent
Exclusion criteria
Exclusion criteria: Known allergy to cysteamine or penicillamine Personal or family history of vitiligo Use of any topical or systemic treatment for melasma within the last 4 weeks Pregnancy or lactation Active skin infection, eczema, or other dermatological conditions affecting the face Known hypersensitivity or allergy to cysteamine hydrochloride, pycnogenol, tranexamic acid, or any ingredients in the wash History of keloid formation or hypertrophic scarring Recent (within 3 months) use of chemical peels, laser therapy, or other procedural treatments on the face Participation in another clinical trial within the past 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in mMASI score Change in melanin index and L index Change in brown spotsTimepoint: Day 0, Week 4, Week 8, Week 12 | — |
Secondary
| Measure | Time frame |
|---|---|
| Participants self-reported satisfaction and tolerability at Week 8 and Week 12. Incidence and severity of local or systemic adverse events throughout the study period. Timepoint: Day 0, Week 4, Week 8, Week 12 | — |
Countries
India
Contacts
Public ContactDr C Divyalakshmi
RENDER SKIN AND HAIR
Outcome results
None listed